Sample interview questions: Can you explain the process of acquiring and analyzing advanced imaging techniques, such as diffusion-weighted imaging or spectroscopy?
Sample answer:
Acquisition of Advanced Imaging Techniques:
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Diffusion-Weighted Imaging (DWI):
- Applies diffusion-sensitizing gradients to quantify water molecule movement in tissues.
- Contrast provided by differences in diffusion rates, reflecting microstructural and functional properties.
- Acquired using specialized MRI sequences with echo-planar imaging (EPI) to minimize motion artifacts.
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Spectroscopy:
- Uses magnetic resonance to identify and quantify specific metabolites within tissues.
- Acquires spectra through localized shimming and excitation techniques.
- Proton magnetic resonance spectroscopy (1H-MRS) is commonly used to evaluate brain metabolism and neurochemical abnormalities.
Analysis of Advanced Imaging Techniques:
DWI Analysis:
* Regions of high water diffusion appear as bright, indicating normal or hypercellular tissue.
* Decreased diffusion appears as dark, indicating restricted water movement in areas of ischemia, injury, or inflammation.
* Quantitative diffusion tensor imaging (DTI) provides additional information on tissue anisotropy, orientation, and fiber tracts. Read full answer
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