Sample interview questions: What is your approach to managing patients with precocious puberty in children and adolescents?
Sample answer:
Approach to Managing Precocious Puberty in Children and Adolescents
1. Assessment and Diagnosis
- Thorough history and physical examination to assess Tanner stage, growth velocity, and any associated symptoms.
- Baseline laboratory testing: gonadotropins, sex steroids, thyroid hormones, adrenal hormones.
- Imaging studies (ultrasound or MRI) to evaluate for central precocious puberty (CPP) or underlying pathology.
2. Etiology Identification
- Central precocious puberty (CPP): Idiopathic (most common), hypothalamic lesions, tumors, congenital adrenal hyperplasia.
- Peripheral precocious puberty (PPP): Gonadal tumors, exposure to exogenous hormones (e.g., steroids, estrogen-containing products).
3. Management
Central Precocious Puberty (CPP):
- GnRH agonists: Suppress gonadotropin release and pubertal progression.
- Monitoring: Regular physical exams, growth velocity charts, bone age assessments, and laboratory testing.
- Transition to adult GnRH therapy: Once near bone maturity to prevent premature closure of growth plates.
- Psychological support: Address emotional and soc… Read full answer
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