How do you assess and manage patients with gastrointestinal disorders related to autoimmune diseases?

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Sample interview questions: How do you assess and manage patients with gastrointestinal disorders related to autoimmune diseases?

Sample answer:

Assessment:

  • Detailed history: Inquiry into symptoms, duration, triggers, aggravating factors, family history of autoimmune diseases.
  • Physical examination: Examination of the abdomen for tenderness, masses, hepatomegaly, ascites; skin examination for rashes, ulcers; joint examination for arthritis.
  • Laboratory tests: Blood tests (autoantibody panels, liver function tests, complete blood count); stool tests (fatty acids, elastase); imaging studies (endoscopy, colonoscopy, MRI/CT scan).

Management:

Medical Therapy:

  • Immunosuppressive medications: To suppress the immune response and reduce inflammation (e.g., azathioprine, methotrexate).
  • Biologic therapies: Targeted therapies that block specific inflammatory pathways (e.g., infliximab, vedolizumab).
  • Anti-inflammatory medications: To reduce inflammation (e.g., corticosteroids, mesalamine).

Nutritional Intervention:

  • Dietary modifications: Avoidance of trigger foods, adherence to a specific diet (e.g., low-FODMAP diet for IBS).
  • Nutritional supplements: To address nutrient deficiencies (e.g., vitamin D, calcium).

Lifestyle Modifications:

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