Sample interview questions: Can you explain your knowledge of the principles of ultrafiltration and fluid removal during dialysis?
Sample answer:
Principles of Ultrafiltration and Fluid Removal During Dialysis
Ultrafiltration
- Process by which water and solutes are removed from blood through a semipermeable membrane.
- Creates a pressure gradient across the membrane, drawing fluid out of the blood.
- Controlled by transmembrane pressure (TMP), which is the pressure difference between the blood compartment and the dialysate compartment.
Fluid Removal
- Primary goal of ultrafiltration during dialysis is to remove excess fluid accumulated due to kidney failure.
- Amount of fluid removed is based on:
- Patient’s fluid status
- Dialysis prescription
- Rate of ultrafiltration
Factors Influencing Ultrafiltration
- Membrane characteristics: Permeability, thickness, and surface area.
- TMP: Higher TMP increases ultrafiltration rate.
- Blood flow rate: Higher blood flow rates increase ultrafiltration rate.
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