Sample interview questions: Can you discuss your knowledge of age-related changes in the immune system of older adults?
Sample answer:
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Decreased immune function: The immune system of older adults is less effective at fighting off infections due to a decline in the production of new immune cells, such as T cells and B cells. This makes them more susceptible to illness and disease.
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Increased inflammation: Older adults experience a chronic state of low-grade inflammation, known as inflammaging. This is thought to be a contributing factor to the development of age-related diseases, such as heart disease, cancer, and Alzheimer’s disease.
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Altered immune response: The immune system of older adults is more likely to respond to threats inappropriately. For example, they may have an exaggerated response to infections, which can lead to tissue damage. Conversely, they may have a weaker response to vaccines, which can make them less effective.
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Changes in the gut microbiome: The gut microbiome is a community of trillions of microbes that live in the digestive tract. These microbes play an important role in immune function. As we age, the composition of the gut microbiome changes, which can lead to a decline in immune function.
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Nutritional deficiencies: Older adults are more likel… Read full answer
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