Sample interview questions: How do you approach the evaluation and management of drug-induced renal impairment in patients with kidney disease?
Sample answer:
- Detailed patient history and physical examination: Document any history of kidney disease, current medications, and recent exposures to nephrotoxic agents. Assess for signs and symptoms of renal impairment, such as oliguria, edema, hypertension, and fatigue.
- Laboratory testing: Obtain serum creatinine, blood urea nitrogen (BUN), and electrolytes to assess renal function. Consider additional tests, such as urinalysis, urine protein-to-creatinine ratio, and cystatin C, to further evaluate renal function and identify the underlying cause of renal impairment.
- Imaging studies: If indicated, order imaging studies, such as ultrasound or computed tomography (CT) scan, to evaluate the kidneys and rule out structural abnormalities.
- Medication review: Carefully review the patient’s current medications, including prescription drugs, over-the-counter medications, herbal supplements, and recreational drugs. Identify any medications that are known to be nephrotoxic or that may have contributed to the renal impairment.
- Discontinuation or dose adjustment of nephrotoxic medications: If possible, discontinue or adjust the dose of any med… Read full answer
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