How do you handle the monitoring and auditing of clinical research data?

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Sample interview questions: How do you handle the monitoring and auditing of clinical research data?

Sample answer:

1. Define Roles and Responsibilities:

  • Delineate the roles and responsibilities of the monitoring and auditing team, including clinical research associates (CRAs), data managers, and auditors.
  • Ensure team members have the necessary training, experience, and expertise to effectively conduct monitoring and auditing activities.

2. Develop a Monitoring Plan:

  • Create a comprehensive monitoring plan that outlines the specific activities to be performed and the frequency of these activities.
  • Tailor the monitoring plan to the specific clinical trial protocol and the associated risks and complexities.

3. Conduct Monitoring Visits:

  • Schedule and conduct monitoring visits to clinical research sites in accordance with the monitoring plan.
  • Review source documentation, including patient medical records, laboratory results, and adverse event reports, to ensure accuracy and completeness.
  • Assess compliance with regulatory guidelines and institutional review board (IRB) requirements.

4. Review Data Quality:

  • Implement data quality control procedures to ensure the accuracy, consistency, and completeness of clinical trial data.
  • Monitor data entry and data management processes to identify and rectify errors or discrepancies.

5. Conduct Audits:

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